Earth, Planetary & Environmental Science
The chemistry, geology, and dynamics of Earth and other planets — from deep crustal processes and surface weathering to environmental change and ecological stress.
All Hypotheses
Abiotic vs Enzymatic PLOOH Regioselectivity as Chemical Fossil of Antioxidant Evolution
The chaotic chemistry of ancient iron reactions may have driven evolution of the precise enzymes that now control cell death.
Ferritin Protein Shell as Kinetic Barrier Controlling Ferrihydrite Fenton Activity
The protein cage surrounding your cells' iron stores may be a safety vault keeping a potent chemical reactor under lock and key.
Pourbaix Stability Field Mapping of Ferrihydrite-Catalyzed PLOOH Production
Ancient rock chemistry could explain exactly where and why iron triggers cancer-linked cell death.
PHREEQC Iron Speciation Model Predicts GSH-Dependent Fenton Activity Amplification
A geology chemistry tool may reveal why iron becomes deadly only in the final stages of a cell's self-destruction.
Fe-S Cluster Cu Displacement (Geochemical Cu-Fe Replacement Series)
Ancient ocean chemistry may explain how copper kills cancer cells from the inside out.
TST Dissolution Kinetics in the Surface-Reaction-Limited Regime of Low Drug-Loading ASDs
A volcano-rock chemistry equation could predict how poorly soluble drugs dissolve from pharmaceutical formulations.
Grambow Rate Law 2 Predicts Competitive Passivation-Erosion Kinetics and Regime Switching in ASD Dissolution
A geology equation used to model volcanic rock dissolving could predict how poorly-soluble drugs release in the body.
Dual Saturation Index Competition Predicts LLPS vs. Crystallization Pathway Switching in Ionizable Drug ASD Dissolution
Equations from volcano science could predict whether experimental drugs dissolve properly or crash out as useless crystals.
FDX1 Redox Potential Tuned to Vent Cu2+/Cu+ Boundary
Ancient deep-sea chemistry may have shaped how copper kills cancer cells today.
Nucleation-Controlled Ostwald Ripening with Polymer Inhibition Predicts ASD Phase Evolution Trajectories
Volcanic rock chemistry could unlock a precise formula for how poorly soluble drugs dissolve in the body.
Melatonin-Induced Diatoxanthin NPQ Buffer in Symbiodiniaceae
Could melatonin help coral's algae partners handle heat by activating a built-in light-protection switch?
H2S-CuS Nanoparticle Feed-Forward Loop
Ancient deep-sea chemistry may hold the key to a new way of killing cancer cells with copper.
Pressure-Fracture Competition Regime Map for ASD Manufacturing Optimization
Volcano science could predict how poorly soluble drugs dissolve — and when manufacturing goes wrong.
Dark Priming — Nocturnal Melatonin Failure Under Nighttime Warming Triggers Bleaching
Warm nights may silently drain corals' chemical defenses before the sun even rises, making bleaching inevitable by dawn.
Dithiolane-Chalcopyrite Ligand Homology
Ancient copper-sulfur chemistry from deep-sea vents may mirror the molecular mechanism that makes copper lethal to cells.
Melatonin-AFMK-AMK Cascade as GSH-Independent Thermal Antioxidant Buffer
Melatonin's chemical cascade might protect corals from heat stress when their main antioxidant system fails.
Evolutionary FDX1-LIAS Reconstruction
Ancient volcanic seafloor chemistry may have shaped the cellular machinery that lets copper kill cancer cells today.